Maintenance of Primary Hepatocyte Functions In Vitro by Inhibiting Mechanical Tension-Induced YAP Activation
Summary: Hepatocytes are the primary functional cells of the liver, performing its metabolic, detoxification, and endocrine functions.Functional hepatocytes are extremely valuable in drug discovery and evaluation, as well as in cell therapy for liver diseases.However, it has been a long-standing challenge to maintain the functions of hepatocytes in